DescriptionIndicationsContraIndicationsDosageWarning/Precautions

TUSSINORE SYRUP

DESCRIPTION

Introduction

DEXTROMETHORPHAN

XX is antitussive agent. Chemically XX is identified as morphinan,3-methoxy-17-methyl-, (9a,13a,14a )-, hydrobrmide. XX is the d isomer of the codeine analog of levophanol. In contrast to the l isomer, dextromethorphan does not possess analgesic or addictive properties, and its principal use is as a cough suppressant.

Category:

  • Drugs acting on the respiratory tract
  • Antitussives
  • Cough sedatives

Primary Characterstics

Dextromethorphan is of Synthetic origin and belongs to Morphine. It belongs to Anti-tussives pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group.The Molecular Weight of Dextromethorphan is 370.30.
Its pKa is 8.3.

Pharmacokinetics

Presystemic metabolism is noted to be 75% ±5 and metabolism is reported extensive by liver. Renal Excretion accounts for > 50% and plasma half life is 2.7-3.3 hr.