Introduction DOCUSATE
XX is a laxative, used in the treatment of constipation or fecal impaction. It acts primarily by increasing the penetration of fluid into faeces, also may affect other intestinal fluid secretions and probably acts both as stimulant and faecal softening agents. XX is also used as an adjunct for bowel evacuation prior to abdominal radiological procedures. |
Category: - Gastrointestinal drugs
- Laxatives
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DICLOFENAC
XX is NSAID (non-steroidal anti-inflammatory drug). XX is a simple phenylacetic acid derivative. It resembles both flurbiprofen and meclofenamate. It reduces fever and inflammation and relieves pain. |
Category: - Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
- Non-opioid analgesics
- Non steroidal anti-inflammatory drugs (NSAIDs)
- Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
- Antirheumatics, topical
- Ophthalmological preparations
- Anti-inflammatory agents
- Non steroidal anti-inflammatory drugs (NSAIDs)
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Primary Characterstics Docusate is of Synthetic origin. . The Molecular Weight of Docusate is 444.60. |
Docusate Sodium also known as Diclofenac, is of Synthetic origin and belongs to Amino Phenyl Acetate. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group.The Molecular Weight of Diclofenac is 318.10. Its pKa is 4. |
Pharmacokinetics Oral absorption of Diclofenac is found to be 47% ±47. Volume of distribution is found to be 0.12 l/kg and plasma protien binding is 99.5%. Presystemic metabolism is noted to be 20% ±20 and metabolism is reported extensive. Renal Excretion accounts for major and plasma half life is 1-2 hr.
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