Introduction
GABAPENTIN
XX is an antiepileptic that is used as an adjunctive treatment of partial seizures with or without secondary generalisation. XX is also used for the treatmnet of neuropathic pain. |
Category: - Anticonvulsants and Antiepileptics
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Primary Characterstics
Gabapentin is of Synthetic origin and belongs to GABA. . The Molecular Weight of Gabapentin is 171.30. Its pKa is 3.7,10.7. |
Pharmacokinetics
Oral absorption of Gabapentin is found to be 30% ±30. Volume of distribution is found to be 57 litre and plasma protien binding is negligible. Renal Excretion accounts for ~ 60 % unchanged and plasma half life is 5 - 7 hr.