Introduction DICLOFENAC FREE ACID
XX is a non-steroidal anti-inflammatory drug (NSAID). XX is only available in the form of dispersible tablets, specifically designed to disintegrate quickly in water yielding a tasteless suspension of it, which is taken orally. The actions and uses are similar to those of diclofenac sodium. |
Category: - Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
- Non-opioid analgesics
- Non steroidal anti-inflammatory drugs (NSAIDs)
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DICLOFENAC
XX is NSAID (non-steroidal anti-inflammatory drug). XX is a simple phenylacetic acid derivative. It resembles both flurbiprofen and meclofenamate. It reduces fever and inflammation and relieves pain. |
Category: - Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
- Non-opioid analgesics
- Non steroidal anti-inflammatory drugs (NSAIDs)
- Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
- Antirheumatics, topical
- Ophthalmological preparations
- Anti-inflammatory agents
- Non steroidal anti-inflammatory drugs (NSAIDs)
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Primary Characterstics Diclofenac also known as Diclofenac free acid, is of Synthetic origin. . |
Diclofenac Sod. also known as Diclofenac, is of Synthetic origin and belongs to Amino Phenyl Acetate. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group.The Molecular Weight of Diclofenac is 318.10. Its pKa is 4. |
Pharmacokinetics Plasma protien binding is 99.7%. Renal Excretion accounts for 60% . Oral absorption of Diclofenac is found to be 47% ±47. Volume of distribution is found to be 0.12 l/kg and plasma protien binding is 99.5%. Presystemic metabolism is noted to be 20% ±20 and metabolism is reported extensive. Renal Excretion accounts for major and plasma half life is 1-2 hr.
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