Introduction
AZITHROMYCIN
The antimicrobial agents or antibiotics develops during the last 60 years are among the most dramatic examples of the advances of science. The remarkably powerful and specific activity of antimicrobial drug is due to their selectivity for highly specific targets that are either unique to micro-organism or much more important in them than in humans. XX belongs to a macrolide antibiotic. Azthromycin is a 15-atom lactone macrolide ring compound. XX is a semisynthetic derivative of Erythromycin obtained by the addition of methylated nitorgen into the lactone ring of Erythromycin. XX is effective against gram positive bacterias. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. XX is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment. |
Category: - Anti-infective drugs
- Antibiotics, systemic
- Other anti-bacterial drugs
- Macrolides
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Primary Characterstics
Azithromycin is of Semi Synthetic origin and belongs to Azalide. It belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.The Molecular Weight of Azithromycin is 785.00. |
Pharmacokinetics
Oral absorption of Azithromycin is found to be 34% ±19. Volume of distribution is found to be 31.1 l/kg and plasma protien binding is 51%. Renal Excretion accounts for < 10% and plasma half life is 68%.